Anemia: Causes, Symptoms, Diagnosis, and
Treatment
Introduction
Anemia is a frequent blood disorder
that impacts millions and millions of people globally. It is caused when there are
not enough healthy red blood cells (RBCs) or hemoglobin in the body to supply
oxygen to the body's tissues. Therefore, the condition often leads to symptoms
of fatigue, weakness and shortness of breath.
This in-depth guide covers anemia in
full, including its forms, causes, symptoms, diagnosis, treatments and
prevention. By knowing anemia, people can do something about it and prevent
this condition from getting out of hand.
What is Anemia?
Anemia is a medical condition that
results from a lack of any of the components in the blood.
·
Red blood
cells (RBCs) -The cells that
carry oxygen to the body parts after it is supplied to the lungs.
·
Hemoglobin – The iron rich protein in RBCs that combines
with oxygen.
When there is not enough RBCs or
hemoglobin, the body, the organs, and the tissues do not get enough oxygen, and
this leads to different health issues.
Global Prevalence
of Anemia
As World Health Organization (WHO)
puts it, approximately 1.62 billion individuals worldwide have anemia, and:
·
Pregnant
women (41.8)
·
Children
aged below five (47.4%)
·
Those women
in their reproductive age (30.2%)
It is more prevalent in developing
nations because of malnutrition and underutilization of healthcare services.
Types of Anemia
Anemia has various types; each type
has the varied cause and treatment.
1.
Iron-Deficiency Anemia
The most
widespread, which is triggered by low intake or absorption of iron. Hemoglobin
is manufactured by use of iron.
Causes:
·
Malnutrition
(deficiency of food containing iron)
·
Blood loss
(menstrual period, ulcers, surgery)
·
Pregnancy
(more iron requirements)
2. Vitamin
Deficiency Anemia (Megaloblastic Anemia)
It happens when the vitamin B12 or
folate (B9), needed to create the RBCs is low.
Causes:
·
Unhealthy
eating (deficiency of B12 or folate)
·
Pernicious
anemia (autoimmune disorder of the absorption of B12)
·
Digestive
problems (celiac disease, Crohn’s disease)
3. Aplastic
Anemia
One of the most severe conditions,
which is rare, but the bone marrow cannot generate enough RBCs, WBCs, and
platelets.
Causes:
·
Autoimmune
disorders
·
Chemotherapy/radiation
treatment
·
Pesticides,
benzene Toxins
4. Hemolytic
Anemia
It happens when RBCs are destroyed
more rapidly than they can be made.
Causes:
·
Genetic
illnesses (sickle cell anemia, thalassemia)
·
Infections
(malaria)
·
Autoimmune
disorders
5. Anemia of
Chronic Disease
Related to chronic diseases including:
·
Kidney
disease
·
Cancer
·
HIV/AIDS
·
Rheumatoid
arthritis
Such conditions disrupt the production
of the RBCs.
Symptoms of
Anemia
Depending on the severity and type of
anemia the symptoms may vary but can include:
·
Tiredness
and Low energy levels
·
Yellowish or
pale skin
·
Breathlessness
·
Lightheaded
or dizziness
·
Cold hands,
cold feet
·
Irregular
pulse (arrhythmia)
·
Headaches
·
Severe pain
in the chest (in rare cases)
Severe Anemia
Complications
When untreated, anemia may cause:
·
Heart
difficulties (swollen heart, heart failure)
·
Problems
during pregnancy (birth before time, birth weight)
·
Impaired
growth of children
·
Higher
chances of infections
Causes and Risk
Factors of Anemia
Primary Causes
1. Dietary Deficiencies- Iron, vitamin B12 or folate deficiency.
2. Chronic Blood Loss - Heavy menstrual periods, ulcers, bleeding of
the gastrointestinal tract.
3. Bone Marrow Disorders – Leukemia, Myelodysplastic syndromes.
4. Genetic Causes – Sickle cell anemia, thalassemia.
Risk Factors
·
Gender- Women (because of menstruation and pregnancy)
·
Age -Infant, small children, and old adults
·
Chronic
Diseases – kidney disease, diabetes, cancer
disease.
·
Unhealthy
Diet Vegetarians/vegans (limited intake of
B12)
·
Genetic
anemias Family History
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Diagnosis of
Anemia
To diagnose anemia doctors, employ a
number of tests:
1. Complete Blood
Count (CBC)
Measures:
·
Hemoglobin levels
(Normal range: 12-16g/dL in women, 13.5-17.5 g/dL in men)
·
Hematocrit (RBCs
percentage in blood)
·
RBC and size
2. Peripheral
Blood Smear
Studies RBC shape and size on a
microscope.
3. Iron Studies
·
Serum ferritin
(measures body stored iron)
·
TIBC (total
iron-binding capacity) & Serum iron
4. Vitamin B12
and Folate Tests
Detects deficiencies.
5. Bone Marrow
Biopsy (for severe cases)
Monitors the functioning of the bone
marrow.
Treatment Options
for Anemia
The kind of anemia and its cause
determines treatment.
1.
Iron-Deficiency Anemia Treatment
·
Ferrous sulfate,
ferrous gluconate Irons supplements
·
Food alterations
(red meat, spinach, lentils, enriched cereals)
·
Treating the
underlying causes (e.g. cessation of blood loss)
2. Vitamin
Deficiency Anemia Treatment
·
B12 injection or
vitamin B12 supplements
·
Vitamin B
supplements
·
Alterations in
nutrition (eggs, milk, leafy vegetables)
3. Aplastic
Anemia Treatment
·
Blood
transfusions
·
Bone marrow
transplant
·
Immunosuppressive
therapy
4. Hemolytic
Anemia Treatment
·
Autoimmune
autoimmune causes Corticosteroids
·
Blood
transfusions
·
Splenectomy (in
severe cases removal of the spleen)
5. Anemia of
Chronic Disease Treatment
·
Managing the
underlying cause of the disease
·
Kidney disease
EPO (erythropoietin) injection
Prevention of
Anemia
1. Eat a Balanced
Diet
·
Animal food: Red
meat, reddish beans, green leafy veggies, nuts.
·
Vitamin C food
sources: Oranges, and bell peppers (increases absorption of iron).
·
B12 sources:
Eggs, dairy and fortified cereals.
·
Folate food:
Lentils, asparagus, avocados.
2. Supplements
(if needed)
·
Pregnancy
vitamins for pregnant women.
·
Iron supplements
(if only ordered).
3. Manage Chronic
Conditions
·
Periodic check-up
for kidney disease, diabetes etc.
4. Avoid
Excessive Blood Loss
·
Treats a heavy
menstrual flow.
·
Treat ulcers or
bleeding of the stomach.
Conclusion
Anemia is a common and mostly
avoidable disorder. Knowledge of the causes, symptoms and treatment can enable
persons to be in charge of their health. However, when you have fatigue,
paleness, or experience dizziness, you should go to a doctor and get diagnosed
appropriately.
Anemia is a treatable or even
preventable condition with the help of a nutrient-rich diet and the control of
underlying conditions, as well as medical consultation in case of need. Be
aware, be healthy!
FAQs About Anemia
Q 1: Is anemia
curable?
Yes, the majority of anemia types can
be treated by changes in the diet, supplements, or medical treatment.
Q2: What is the
recovery time of anemia?
Mild ones can be cured in weeks using
iron supplements, whereas chronic cases of anemia can last a long time to be
treated.
Q3: Is anemia
life threatening?
Untreated anemia may cause heart
failure or organ failure especially when this is severe, however early
treatment eliminates complications.
Q4: Is it
possible to have adequate iron in the vegetarian diet?
Yes, in combination with the plant
iron sources (beans, spinach) and vitamin C which helps to increase absorption.
Q5: does anemia
make you gain weight?
No, it might decrease physical
activity, which indirectly affects weight.
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