The Immune System: Your Body’s Defense
Mechanism
Introduction
To protect the body from bacteria,
viruses, fungi and toxins, the immune system uses a network of cells, tissues
and organs. With a weak immune system, infections that would normally be
harmless could become dangerous for your life. Apart from identifying and
tackling pathogens, this defense process also allows the body to act more
swiftly if it meets these pathogens again.
This article will explain the immune
system clearly, including what it consists of, how it operates, its various
types, related disorders and how to increase its strength.
Components of the
Immune System
There are two parts to the immune
system: the innate and the adaptive system. They both play their part to keep
the body healthy.
1. Innate Immune
System
The body’s first defense is the innate
immune system. It provides a quick response to pathogens, though immunity won’t
last for long. It consists of the following:
·
Physical
Barriers:
o
Skin serves as a
shield for our bodies.
o
They help capture
and remove germs from the mouth and lung passages.
o
Stomach acid:
Destroys any germs that come with our food.
·
Cellular
Defenses:
o
NK Cells: Recognize and kill cells that are infected
with a virus or are cancerous.
o
Both Macrophages
and Neutrophils take in and destroy threats in the body.
o
Dendritic
Cells: Collect antigens and give them to
cells of the adaptive immune response.
·
Chemical
Defenses:
o
Cytokines are
proteins that help manage the body’s immune actions.
o
Complement
System: A type of proteins that increases the ability to destroy pathogens.
o
Interferons are
proteins that slow down how viruses reproduce.
2. Adaptive
Immune System
The adaptive system specializes in
fighting infections and protects the body for a long time. It includes:
·
Lymphocytes
(B Cells & T Cells):
o
B Cells: Make
antibodies that destroy pathogens.
o
T Cells:
§ T helper cells (CD4+) help other immune cells
to take action.
§ CD8+ T Cells: Get rid of cells that are
infected.
§ Regulatory T Cells are in charge of reducing
the immune system’s activity.
·
Antibodies
(Immunoglobulins):
o
They are Y-shaped
proteins that recognize certain foreign substances.
o
The types are
IgG, IgM, IgA, IgE and IgD.
o
Keep in mind
previous infections to react quicker if you are exposed again.
How the Immune
System Works
There are several stages that the
immune system goes through.
1. Detection of
Pathogens
·
Pathogens may
enter the body if they get into cuts, are inhaled or swallowed.
·
These cells
detect general patterns found in pathogens.
2. Immediate
Innate Response
·
Phagocytes
encounter and get rid of harmful invaders.
·
Inflammation
happens which makes the affected area swell and brings more immune cells.
3. Adaptive
Immune Activation
·
Dendritic cells
give T and B cells the antigens they recognize.
·
Helper T cells
cause B cells to make antibodies.
·
These T cells
destroy infected cells in the body.
4. Memory
Formation
·
There are still
Memory B and T cells left, ensuring we are protected over a long period.
Types of Immunity
1. Active
Immunity
·
Created by your
body after contact with a pathogen or by receiving a vaccination.
·
It can continue
to affect someone for years.
2. Passive
Immunity
·
A short-term
defense against diseases provided by antibodies in breast milk or from
injections.
3. Natural vs.
Artificial Immunity
·
Natural
Immunity: Those who have natural immunity were
exposed to the virus and developed immunity.
·
Artificial
Immunity: Vaccines are the main cause of
Artificial Immunity.
Immune System
Disorders
A dysfunctional immune system can
bring about different disorders.
1. Autoimmune
Diseases
·
The body’s
immune system starts attacking its own tissues.
·
Examples:
o
Rheumatoid
Arthritis is a case where joints are attacked.
o
When you have
Type 1 Diabetes, your pancreatic beta cells are destroyed.
o
Lupus affects
many organs in the body.
2.
Immunodeficiency Disorders
·
Decreased ability
of the immune system.
·
The first group
(Congenital) is caused by genetics such as the case of “Bubble Boy Disease”
(SCID).
·
Sometimes,
secondary (Acquired) occurs due to illnesses such as HIV/AIDS or treatments
such as chemotherapy.
3. Allergies
·
Reacting strongly
to things that are not dangerous (such as pollen or peanuts).
·
When IgE
antibodies are present, histamine gets released and causes sneezing, rashes or
a dangerous condition called anaphylaxis.
4.
Hypersensitivity Reactions
·
When the immune
system acts too strongly, it is known as type I-IV immune response.
·
Example: Anaphylaxis which is a serious allergic
reaction.
Ways to
Strengthen the Immune System
Following a healthy lifestyle
strengthens your immune system.
1. Nutrition
·
Vitamins
& Minerals is...
o Peppers and citrus fruits are good sources of
vitamin C.
o Vitamin D comes from the sun and from eating
fatty fish.
o Zinc can be found in nuts, seeds and meat.
·
Yogurt and
kefir are foods that contain probiotics and support your gut’s immune system.
2. Exercise
·
When we exercise
moderately, our blood circulation and immune system activity increase.
3. Sleep
·
Getting 7-9 hours
of sleep each night enhances your body’s ability to remember how to fight
diseases.
4. Stress
Management
·
Long-term stress
can reduce your body’s ability to defend itself (take up meditation and yoga to
help).
5. Hydration
& Hygiene
·
Drinking water
helps cleanse the body and washing your hands helps stop infections.
6. Vaccination
·
Allows the immune
system to spot and defend the body against pathogens.
Conclusion
The immune system is an amazing
network that defends the body from lots of different dangers. Knowing the
parts, roles and possible problems of the body shows us how important it is. Taking
care of our health can help our immune system and make us feel healthier.
No matter if its system is natural or
learned, the immune system is one of the most advanced in our bodies, always
adjusting to keep us safe from new pathogens.
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